New Study Shows Importance of Key Enzyme in Skin Diseases
by April Maguire
If you or someone you know would like to learn more about healthy skin, please feel free to schedule a consultation or contact one of our representatives today!
Keeping your skin healthy is difficult under the best of circumstances, and if you have an autoimmune disease that impacts the skin, it can be nearly impossible. Depending on the condition, autoimmune diseases can cause your skin to thicken, shed, blister or become discolored. The key to keeping these kinds of diseases at bay, however, is understanding how they function, and for the first time, scientists think they've gained a better knowledge of what causes a condition known as epidermolysis bullosa acquisita to result in severe and painful blistering.
The Importance of Granzyme B
Epidermolysis bullosa acquisita may be a rare disorder, but it's incredibly troublesome for those affected by it. The hallmark of this condition is pus- or blood-filled blisters along the surface of the skin, typically occurring on the hands, feet, elbows and knees. Currently, there are no reliable treatments for EBA, and typical medications include anti-inflammatory agents, immune suppressants and oral corticosteroids. Unfortunately, finding the right combination of these drugs can be difficult, and patients often suffer with the condition for years.
Fortunately, a new study published in the journal "Scientific Reports" may offer a new solution to EBA and other autoimmune disorders like it. For the study, researchers looked at the role that an enzyme called Granzyme B played in people suffering from EBA, and what they discovered for a strong, direct correlation. According to the result of the study, EBA sufferers had significantly higher levels of Granzyme B in their systems. Similarly, patients with two other autoimmune disorders, dermatitis herpetiformis and bullous pemphigoid, were also found to have increased Granzyme B production.
So what is Granzyme B? According to the researchers, it's an enzyme that helps with cell-mediated apoptosis, or natural cell death. In other words, it helps your cells to shut down before they're shed and replaced with newer ones. What the study revealed, however, was that high concentrations of Granzyme B had an incredibly detrimental impact on the skin.
Through in vitro experiments, the team found that a build-up of Granzyme B caused a noticeable separation of skin cell layers. This kind of separation could explain how blisters are formed in patients suffering from epidermolysis bullosa acquisita. Even more telling, however, was the fact that when a Granzyme B inhibitor was introduced to the samples, the skin separation was prevented.
Ultimately, this new study gives some hope to people dealing with epidermolysis bullosa acquisita. Even though this line of research is still in its early stages, it could lead to breakthrough treatments for people suffering from a wide array of autoimmune disorders.
If you or someone you know would like to learn more about healthy skin, please feel free to schedule a consultation or contact one of our representatives today!
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Addressing Your Pre-Wedding Skincare Needs
Homemade Recipes for Healthy Hair and Skin
4 Amazing Ingredients to Include in DIY Skincare Treatments
Can You Improve Your Skin by Doing Yoga?
The Benefits of Yogurt for Skin (Internally and Externally)
9 Top Foods for Terrific Skin
The Future of Dermatology Procedures 2017 Scholarship – Healthy Skin Portal
11 Easy Ways to Keep Skin Looking Terrific
Tips for Eating Chocolate and Not Harming Your Skin
Summer Skincare Essential: Face and Body Scrubs
Seven Foods for Terrific Skin
6 Amazing Tricks to Improve Your Skin
What are the Best Treatments for Your Skin?
Are Your Daily Habits Destroying Your Skin?
ASA Offers Up Seven Principles for Healthy Skin
Does the Wrong Mix of Skin Bacteria Cause Acne?
Can Probiotics Help Acne?
How Do Celebrities Keep Their Skin Looking Great?
What Should You Be Eating to Help Your Skin?
7 Korean Beauty Products That You Should Own
It's Time to Get Ready for Great Looking Summer Hair and Skin
Six Skincare Tips from Different Cultures
Top Beauty Tips on a Budget
Three Simple Mistakes That Could Be Ruining Your Skin
Essential Ingredients for a Great Complexion
Six Foods to Help Hydrate Your Skin
New Ideas for Morning Skincare
The Surprising New K-Beauty Super Ingredient: Watermelon
Five Simple Foods to Boost Your Skin
Keeping Your Skin Healthy in the Summer
Top Skincare Tips for Guys
5 Amazing Skincare Products That Are Cruelty-Free
The Best Selling Beauty Product on Amazon Will Surprise You
How Does Stress Impact Your Skin?
4 Acids That Will Actually Help With Your Skin
Want Better Skin? Here Are Six Foods to Help You Get It
What You Need to Do to Keep Great Skin for Life
How Much Skin Should Be Removed With a Mole?
Is Your Pillowcase Destroying Your Skin?
Jessica Alba's Skincare Line
Fall and Winter Skincare for Men
How to Create An Effective Daily Skincare Routine
4 Supplements You Should Be Using for Your Skin
Collagen Powder: The Next Skincare Secret or Another Passing Fad?
How Do You Pick The Right Moisturizer?
7 Ways to Protect Your Skin This Winter
8 Top Smoothie Ingredients for a Radiant Complexion
Five Water-Rich Foods Your Skin Needs
Uncovering the Secret of the Japanese 4-2-4 Cleansing Technique
Avocados: A Very Healthy Fruit
Using Superfood-Enhanced Beauty Products
Six Tips to Avoid Bad Skin Days
New Technology Allows Restoring of Your Own Collagen and Elastin
How to Slow the Skin's Aging Process
Important Supplements for Aging Skin
How Dermatologists Take Care of Their Skin
How Traditional Thanksgiving Foods Affects Your Skin
How to Use Chocolate to Get Better Skin
Simple Life Hacks for Your Skin
Natural Remedies to Keep Your Skin Looking Great This Winter
Organic Skin Care on the Rise
Little-Known Skincare Rules That Everyone Should Follow
Probiotics for Great Skin
A Supermodel's Skincare Secrets
Your Skin-Friendly Grocery List
Could Oil Cleansing Save Your Skin?
Beauty Device Market Set to Rise in Coming Years
How to Keep Your Skin Radiant Even in Winter
Night Cream: The Key to Healthy Winter Skin
Beauty Brands Harnessing the Power of Superfoods
4 Ways Alcohol Damages Your Skin
How Probiotics Help Skin
4 Ways to Maintain Flawless Skin in the Dead of Winter
Microbiome Imbalance in Gut May Lead to Acne
The Best Diet for Terrific Hair and Skin in Winter
Is Coconut The Key to Healthier Skin?
Celebrities Struggle with Acne Too
Six Ways to Improve Your Skin
What You Need for a Skin-Friendly Diet
Five Simple Steps to Healthier Skin
Why Vaseline is Still An Excellent Choice for Skincare
Dermaplaning Myths Debunked
What Are The Best Ways to Deal with Blackheads?
Say Goodbye to Dry Skin
Yoga Can Help Your Skin
Using a K-Beauty Routine to Tackle Eczema
What is Your Skin Barrier and How Can You Protect It?
Five Top Foods for Maintaining Healthy Skin
Little-Known Tricks to Give You Better Skin
How Can Ayurveda Principles Help Your Skin?
Five Foods with Top Beauty Benefits
Get Your Skin Ready for Summer
3D Printing Could Replace Skin Grafts
Adjusting Your Vitamin D Levels During The Summer
Using Orange Peels to Improve Your Skin
Carotenoids: The Secret to Healthy Skin
Your Greatest Ally in the Quest for Flawless Skin: Vitamin C
Japanese Skincare Routine May Outshine Popular Korean Routine
Six Ways to Help Your Skin Beat The Summer Heat
Consume Fruit for Radiant Skin
New Study Shows Importance of Key Enzyme in Skin Diseases
Bad Habits to Break for Great-Looking Skin
Papaya for Skin Care
Five Fun Ways to Get More Watermelon in Your Diet
Busting Skincare Myths
Tips for Achieving Glowing Skin
Giving Your Skin That Alkaline Glow
Vitamin C for Healthy Skin
Using Collagen to Improve Your Skin
What Can Mushrooms Do For Your Skin?
Vitamin E: The Secret to Beautiful Skin
Regular Facials Keep Skin in Top Condition
Top Foods for Glowing Skin
The Power of Magnetic Masks
Five Top Vitamins for Great Hair, Skin and Nails
When to Ditch Old Makeup
What Do Experts Recommend for Your Skin?
Maple Leaf Extract May Prove The Next Anti-Wrinkle Miracle Ingredient
Essential Winter Skin Care
Does Your Skincare Routine Need a Cat-Face Towel? Absolutely!
Six Overnight Skincare Products for Daytime Beauty
How a 22-Year-Old Created an Empire of Vegan Skincare Products
Revolutionary New Process Could Help Regrow Damaged Skin
Cinnamon for Skin Health
Does The Key to Beautiful Skin Lie in Your Gut?
How to Have Truly Healthy Skin
Five Tricks Everyone Should Know to Keep Their Skin Looking Great
The New Three-Minute Skincare Routine
Nine Foods That Improve Skin
Cold Weather Skin Tips
Do You Want Amazing Skin? Here's Your Beverage Guide
Drinking Coffee Can Actually Help With Rosacea
How Hypertension Can Destroy Your Skin